Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?

Table 5

HLA typing and time points for follow-up in DAISY (general population).

(a) Eligible HLA types^†	DRB1^*03-DQB1^*02/DRB1^*04-DQB1^*0302, and negative for DRB1^*0403
	DRB1^*04-DQB1^*0302/DRB1^*04-DQB1^*0302, and negative for DRB1^*04034
	DRB1^*03-DQB1^*02/DRB1^*03-DQB1^*02
	DRB1^*04-DQB1^*0302/DRB1^*01-DQB1^*0501, and negative for DRB1^*0403
	DRB1^*04-DQB1^*0302/DRB1^*08-DQB1^*0402
	DRB1^*04-DQB1^*0302/DRB1^*09-DQB1^*0303
(b) Time points for blood samples	9, 15, and 24 and thereafter annually
(c) Questionnaires	Filled out at the clinical visits at 9, 15, and 24 months of age, and thereafter annually
(d) Rectal swabs and salvia:	At 9, 15, and 24 months of age, and annually thereafter

No HLA typing for siblings of a child with T1D.