Luminex and Other Multiplex High Throughput Technologies for the Identification of, and Host Response to, Environmental Triggers of Type 1 Diabetes

Figure 2

Luminex bead arrays could be used to detect different classes of environmental triggers. (a) Protein(s), (b) monoclonal (MAb) or polyclonal (PAb) antibodies, (c) viruses, (d) bacterial cell wall components, (e) DNA from virus/bacteria, and (f) chemicals/drugs can be covalently coupled to the beads. Coupled entities can be detected using fluorescently labeled appropriate detection agents.