BioMed Research International / 2015 / Article / Tab 2

Research Article

Prognostic Value of MRS Metabolites in Postoperative Irradiated High Grade Gliomas

Table 2

Cox regression survival analysis or RFS with age and MRS parameters. All significant parameters from univariate analysis were entered into the multivariate analysis to create the final model (Wald Chi- = 25.03, < 0.001).

VariablesHR (95% CI)HR (95% CI)
UnivariateMultivariate

Cho0.87
Cr0.70
NAA1.23 (1.08, 16.39)0.045
MI0.81
Cho/Cr (baseline)2.94 (1.22, 9.51)0.0012.38 (1.17, 8.78)0.003
Cho/Cr (6 months)1.54 (1.03, 12.76)0.0211.29 (1.08, 11.33)0.042
NAA/Cr0.31
MI/Cr0.72
Age6.85 (2.57, 11.36)0.0015.44 (2.11, 12.26)0.001

Abbreviations: DFS: Disease Free Survival Interval; Cho: choline; Cr: creatine; MI: myo-inositol; NAA: N-acetyl aspartate.