Duck RIG-I CARD Domain Induces the Chicken IFN-β by Activating NF-κB

Table 2

The features of retinoic acid inducible protein I in the duck.

Name	Region/site (aa)	Note
CARD_RIG-I_1	2–90	Caspase activation and recruitment domain found in RIG-I, first repeat
CARD_RIG-I_2	99–184	Caspase activation and recruitment domain found in RIG-I, second repeat
DEXDc	261–413	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region
HELICc	607–742	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins; this domain is found in a wide variety of helicases and helicase related proteins
RIG-I_C-RD	807–926	C-terminal domain of RIG-I
ATP binding site	270–274, 706, 727, 731, 733	Chemical binding
Putative Mg++ binding site	375–378	Ion binding
RNA binding site	511-512, 515, 519	Nucleotide binding
RD interface	519, 522-523, 536-537, 540	Polypeptide binding
Helicase domain interface	554-555, 557–560, 563, 567	Polypeptide binding
Nucleotide binding region	636–639, 663-664, 698–700	Chemical binding

Note. Protein_id: “ACA61272.1”; protein full length: 1–933 aa; organism: “Anas platyrhynchos.”