Research Article
Identification and Biological Characterization of Leishmania (Viannia) guyanensis Isolated from a Patient with Tegumentary Leishmaniasis in Goiás, a Nonendemic Area for This Species in Brazil
Figure 6
Photomicrographs of lesions caused by L. (V.) braziliensis WSS5 and L. (V.) guyanensis PLR6 in IFNγ-deficient C57BL/6 mice. Mice were inoculated with 5 × 106 parasites in stationary phase of growth, and six weeks after infection the histopathology of footpad lesions was evaluated after H&E staining. (a) Nonulcerated lesion in mouse infected with L. (V.) braziliensis WSS5 isolate, (b) ulcerated lesion in mouse infected with L. (V.) guyanensis PLR6 (the circle shows part of the ulceration that contains mononuclear cells and parasites showed in (d)), (c) mononuclear cell infiltrate with presence of parasites of L. (V.) braziliensis WSS5 (black arrow), and (d) mononuclear cells infiltrate with presence of parasites of L. (V.) guyanensis PLR6 (black arrow).
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