Predicting Drug-Target Interactions via Within-Score and Between-Score

Figure 3

Drug-target pair space. Unapproved DTPs are marked by cyan crosses. Approved DTPs of drug-centered, target-centered, single, and multiple motifs are marked by red circles, green triangles, yellow diamonds, and purple squares, respectively. , , and denote the first three principal components, respectively.

(a)

(b)