Prognostic Value of Homotypic Cell Internalization by Nonprofessional Phagocytic Cancer Cells
Table 1
Clinical characteristics of the head and neck squamous cell carcinoma cohorts.
All HNSCC
Early disease Adjuvant RCT
Advanced disease Definitive RT
Metastatic disease
Neoadjuvant RCT
Adjuvant RCT Center/invasion front
321
62
52
29
35
143
Gender ()
Male
274
(85.4)
51
(82.3)
(15.9)
43
(82.7)
(13.4)
28
(96.6)
(8.7)
32
(91.4)
(10)
120
(83.9)
(37.4)
Female
47
(14.6)
11
(17.7)
(3.4)
9
(17.3)
(2.8)
1
(3.4)
(0.3)
3
(8.6)
(0.9)
23
(16.1)
(7.2)
Age (years)
Median (95% C.I.)
54.3
(53.9–55.7)
51.0
(49.4–53.3)
56.0
(53.2–58)
53.0
(49.3–55)
52.5
(51.3–54.5)
58.0
(56.2–59.2)
Local failure time (months)
Median (95% C.I.)
50.0
(58.3–69.4)
67.0
(72.1–111)
42.0
(44.9–72.4)
51.0
(48.8–83.9)
87.0
(74.1–96.6)
32.0
(34.5–46.1)
Time to metastatic disease (months)
Median (95% C.I.)
53.0
(61.7–73)
81.5
(82–121.7)
42.0
(44.7–72.4)
61.0
(51.3–85.7)
90.0
(77.2–99.6)
37.5
(37–48.3)
Overall survival time (months)
Median (95% C.I.)
54.0
(63.5–74.6)
81.5
(82–121.7)
44.0
(47.6–74.2)
61.0
(53.8–89.3)
90.0
(77.5–99.8)
41.0
(39.9–51)
T stage ()
T1
59
(18.4)
13
(21)
(4)
0
0
(0)
7
(24.1)
(2.2)
3
(8.6)
(0.9)
36
(25.2)
(11.2)
T2
105
(32.7)
30
(48.4)
(9.3)
2
(3.8)
(0.6)
8
(27.6)
(2.5)
9
(25.7)
(2.8)
56
(39.2)
(17.4)
T3
78
(24.3)
14
(22.6)
(4.4)
25
(48.1)
(7.8)
6
(20.7)
(1.9)
6
(17.1)
(1.9)
27
(18.9)
(8.4)
T4
79
(24.6)
5
(8.1)
(1.6)
25
(48.1)
(7.8)
8
(27.6)
(2.5)
17
(48.6)
(5.3)
24
(16.8)
(7.5)
N stage ()
N0
68
(21.2)
23
(37.1)
(7.2)
5
(9.6)
(1.6)
0
(0)
(0)
7
(20.0)
(2.2)
38
(26.6)
(11.8)
N1
55
(17.1)
17
(27.4)
(5.3)
4
(7.7)
(1.2)
4
(13.8)
(1.2)
2
(5.7)
(0.6)
29
(20.3)
(9)
N2
186
(57.9)
22
(35.5)
(6.9)
41
(78.8)
(12.8)
23
(79.3)
(7.2)
25
(71.4)
(7.8)
69
(48.3)
(21.5)
N3
12
(3.7)
0
(0)
(0)
2
(3.8)
(0.6)
2
(6.9)
(0.6)
1
(2.9)
(0.3)
7
(4.9)
(2.2)
M stage ()
M0
237
(73.8)
62
(100.0)
(19.3)
39
(75.0)
(12.1)
6
(20.7)
(1.9)
32
(91.4)
(10)
98
(68.5)
(30.5)
M1
84
(26.2)
0
(0.0)
(0)
13
(25.0)
(4)
23
(79.3)
(7.2)
3
(8.6)
(0.9)
45
(31.5)
(14)
Grading ()
G1/2
176
(54.8)
37
(59.7)
(11.5)
37
(71.2)
(11.5)
15
(51.7)
(4.7)
27
(77.1)
(8.4)
60
(42)
(18.7)
G3/4
145
(45.2)
25
(40.3)
(7.8)
15
(28.8)
(4.7)
14
(48.3)
(4.4)
8
(22.9)
(2.5)
83
(58)
(25.9)
UICC97 ()
1
15
(4.7)
6
(9.7)
(1.9)
0
(0)
(0)
0
(0)
(0)
1
(2.9)
(0.3)
8
(5.6)
(2.5)
2
30
(9.3)
13
(21)
(4)
0
(0)
(0)
1
(3.4)
(0.3)
2
(5.7)
(0.6)
14
(9.8)
(4.4)
3
61
(19)
17
(27.4)
(5.3)
7
(13.5)
(2.2)
2
(6.9)
(0.6)
2
(5.7)
(0.6)
33
(23.1)
(10.3)
4
215
(67)
26
(41.9)
(8.1)
45
(86.5)
(14)
26
(89.7)
(8.1)
30
(85.7)
(9.3)
88
(61.5)
(27.4)
Values behind the first bracket are relative values within the subcohort and values behind the second bracket are relative values of the total cohort. Confidence interval: C.I.
