How to Use SNP_TATA_Comparator to Find a Significant Change in Gene Expression Caused by the Regulatory SNP of This Gene’s Promoter via a Change in Affinity of the TATA-Binding Protein for This Promoter

Algorithm 1

IF   is statistically significantly greater than ,

THEN   is “there is an excess of the minor allele of a given gene versus the ancestral allele”;

     ELSE  [IF   is statistically significantly less than ,

        THEN   is “there is a deficiency of the minor allele of this gene versus the ancestral allele”];

OTHERWISE   is “alteration of the expression of this gene is insignificant”.