Identification of Reference Genes in Human Myelomonocytic Cells for Gene Expression Studies in Altered Gravity

Figure 5

Coefficient of variation calculation for the ABC transporter genes. This bar chart displays the coefficient of variation (CV) in % of the 47 ABC transporter genes across the gravity conditions for the 19th DLR PFC (H/W, 1 g, 1.8 g, μg) and TEXUS-49 (H/W, BL, μg). A lower value corresponds to higher stability in gene expression. (a) 19th DLR PFC: all calculated CV values are below the threshold of 50% and fulfill the criterion. (b) TEXUS-49: three genes show CV values higher than 50% and were excluded from further analyses. The numbers correspond to the ABC transporters listed in supplementary Table 2. Genes that were further analyzed are labeled and marked in bold (ABCC1, ABCC4, ABCD4, ABCF2, and TAP2).

(a)

(b)