miR-125b Suppresses Proliferation and Invasion by Targeting MCL1 in Gastric Cancer

Figure 1

miR-125b expression levels are frequently downregulated in human gastric cancer. (a) Relative expression of miR-125b in 7 cell lines derived from gastric cancer and one nonmalignant gastric cell line (GES-1) was determined by qRT-PCR. The error bars represent the standard deviations (SD) from triplicates of one representative experiment. and . (b) miR-125b expression was detected in 36 gastric cancer patient tumors by qRT-PCR. The error bars represent the standard deviations (SD) from triplicates of one representative experiment. . Survival curves of (c) OS and (d) DFS according to miR-125b expression. Whether miR-125b expression levels were high or low was determined using the Kaplan-Meier method and evaluated using the log-rank test.

(a)

(b)

(c)

(d)