Pharmacokinetics Interaction between Imatinib and Genistein in Rats

Figure 1

Extracted ion chromatograms for (a) blank rat plasma, (b) blank rat plasma spiked with imatinib (10 μg/mL), N-desmethyl imatinib (0.500 μg/mL), and IS (carbamazepine), and (c) rat plasma sample after oral administration of single dosage 30 mg/kg imatinib. (1) Imatinib, (2) N-desmethyl imatinib, and (3) IS (carbamazepine).

(a)

(b)

(c)