Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 369179, 7 pages
Research Article

Association between Hyperuricemia and Metabolic Syndrome: An Epidemiological Study of a Labor Force Population in Taiwan

1Department of Neurology, Show Chwan Memorial Hospital, Changhua County 50008, Taiwan
2Department of Neurology, Chang Bing Show Chwan Memorial Hospital, Changhua County 50544, Taiwan
3Department of Exercise and Health Promotion, College of Education, Chinese Culture University, Taipei City 11114, Taiwan
4Physical Examination Center, Show Chwan Memorial Hospital, Changhua County 50008, Taiwan
5Division of Allergy, Immunology and Rheumatology, Chung Shan Medical University, Taichung City 40201, Taiwan
6Department of Public Health, College of Medicine, Fu-Jen Catholic University, New Taipei City 24205, Taiwan
7Sleep Center, Chang Bing Show-Chwan Memorial Hospital, Changhua County 50544, Taiwan
8School of Public Health, National Defense Medical Center, Taipei City 11490, Taiwan
9Department of Nursing, Meiho University, Pingtung County 91202, Taiwan
10Department of Health Business Administration, Meiho University, Pingtung County 91202, Taiwan

Received 12 June 2014; Accepted 26 November 2014

Academic Editor: Yi Liu

Copyright © 2015 Cheng-Yu Wei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The increasing prevalence of metabolic syndrome (MetS) has become an important issue worldwide. Metabolic comorbidities of hypertension, obesity, and hyperlipidemia are shown as important risk factors for incident gout. The purpose of this study was to investigate the relationship between hyperuricemia and MetS. This is a cross-sectional study. The effective sample included 21,544 individuals who received worker health examinations at a local teaching hospital in Changhua County from 2008~2012. We used multiple logistic regression analysis to investigate the influences of hyperuricemia on MetS. The results showed that individuals with MetS had significantly higher blood pressure, fasting plasma glucose, triglycerides, waist circumference, and high-density lipoprotein cholesterol than those without MetS . Multiple logistic regression analysis revealed hyperuricemia to be an important factor of MetS. The risk of developing MetS is higher with high levels of serum uric acid (SUA) and the odds ratio (OR) of having MetS is 4.98 times higher for Tertile 3 than for Tertile 1 (95% CI = 4.16–5.97) and 4 times higher for Quartile 4 than for Quartile 1 (95% CI = 3.59–4.46). In conclusion, males are more likely to develop MetS than females, and the risk of having MetS increases with age and SUA concentration.