Research Article
A Functional Variant at miR-520a Binding Site in PIK3CA Alters Susceptibility to Colorectal Cancer in a Chinese Han Population
Table 1
General characteristics of colorectal cancer cases and controls.
| | Cases () | Controls () | |
| Age (mean ± SD), years | 60.1 ± 12.3 | 60.7 ± 12.9 | 0.506 | Gender | | | | | | Male | 216 | 56.0% | 229 | 58.1% | 0.563 | Female | 170 | 44.0% | 165 | 41.9% | Smoking | | | | | | Never | 262 | 67.9% | 276 | 70.1% | 0.536 | Ever | 124 | 32.1% | 118 | 29.9 | Family history of cancer | | | | | | No | 332 | 86.0% | 360 | 91.4% | 0.023 | Yes | 54 | 14.0% | 34 | 8.6% | Tumor site | | | | | | Colon | 212 | 54.9% | | | | Rectum | 174 | 45.1% | | | | Tumor stages | | | | | | I | 38 | 9.8% | | | | II | 173 | 44.8% | | | | III | 135 | 35.0% | | | | IV | 40 | 10.4% | | | |
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