BioMed Research International

Review Article

Utility of MicroRNAs and siRNAs in Cervical Carcinogenesis

Table 1

Differentially expressed profile microRNAs in normal squamous epithelium, CIN1-3, and CC.


MicroRNAs expression	Normal tissue	CIN1–CIN3	CC	Reference

miR-26a, miR-143, miR-145, miR-99a, miR-203, miR-513, miR-29a, miR-199a	Upregulated	Downregulated	Downregulated	Pereira et al. [4]
miR-106a, miR-205, miR-197, miR-16, miR-27a, miR-142-5p	Upregulated	Downregulated	Downregulated
miR-522, miR-512-3p	Upregulated	Upregulated	Downregulated
miR-148a, miR-302b, miR-10a, miR-196a, miR-132	Downregulated	Upregulated	Upregulated

miR-155, miR-92a, miR-92b, miR-224, miR-221, miR-222, miR-31, miR-182, miR-106a, miR-17, miR-20a, miR-20b, miR-15b, miR-16, miR-25, miR-185, miR-93	Downregulated	Downregulated	Upregulated	Li et al. [5]
let-7b, miR-145, miR-126, miR-199a-3p, miR-195, miR-29a, miR-375, miR-10b, miR29c, miR-218, miR-424, miR-100, miR-125b, miR99a	Upregulated	Upregulated	Downregulated	Li et al. [5]

miR-192, miR-135b, miR-101, miR-191, miR-34c-5p, miR-150, miR-125a-5p, miR-30a, miR-143, miR-146b-5p, miR-181b, miR-7g, miR-26a, miR-29a, miR-29c, miR-29b, miR-10a, miR-29a, miR-145	Downregulated	Upregulated “early transient”	Upregulated “early transient”	Wilting et al. [6]
miR-205, miR-27a, miR-27b, miR-221, miR-193a-3p, miR-212, miR-770-5p, miR-484, miR-636	Upregulated	Downregulated “early transient”	Downregulated “early transient”
miR-28-5p, miR-338-5p, miR-206, miR-200a, miR-92b, let-7i, miR-181d, miR-92a, miR-30e, miR-34b, miR-592, miR-19b, miR-106b, miR-595, miR-34a, miR-25, miR-146a, miR-21	Downregulated	Upregulated “early continuous”	Upregulated “early continuous”
miR-203, miR-638, miR-370, miR-575, miR-193b, miR-149, miR-210, miR-622, miR-23b, miR-493, miR-296-5p, miR-671, miR-134, miR-365	Downregulated	Downregulated	Upregulated “early continuous”
miR-30c, miR-425, miR-24, miR-331-3p, miR-151-3p, miR-107, miR-652, miR-17, miR-9, miR-185, miR-339-5p, miR-18a, let-7-d, miR-17, miR-30d, miR-130b, miR-15a, miR-106a, miR-19a, miR-200c, miR-20b, miR-363, miR-155, miR-141, miR-93, miR-15b, miR-16	Downregulated	Upregulated “late”	Upregulated “late”
miR-125b, miR-375, miR-99a, miR-188-5p, miR-148a, miR-671-5p, miR-199b-3p, miR-513b, miR-378, miR-195, miR-486-5p, miR-26b, miR-376a, miR-199a-5p, miR-497, miR-100, miR-660, miR-218	Upregulated	Upregulated	Downregulated “late”