The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats

Table 2

Effect of treating diabetic rats with Moringa seeds powder for 4 weeks on immunoglobulins, IL-6, and HbA_1c.

Parameters; mg/dL	Treatments; statistics	G1; −ve control	G2; +ve control	G3; 50 mg; Moringa	G4; 100 mg; Moringa
IgG mg/dL	Mean ± SE; LSD 0.05 = 8.048	534.00 ± 2.12^a	753.00 ± 3.24^d	636.17 ± 3.45^b	579.83 ± 2.16^c
	-test		−52.4	23.3	36.2
IgA mg/dL	Mean ± SE; LSD 0.05 = 10.305	102.83 ± 3.47^a	358.17 ± 2.57^d	231.33 ± 3.14^b	175.17 ± 4.26^c
	-test		−47.5	29.2	35.9
Serum; IL-6; pg/mL	Mean ± SE; LSD 0.05 = 1.989	3.400 ± 0.44^a	21.58 ± 1.07^d	13.91 ± 0.60^b	8.35 ± 0.29^c
	-test		−16.3	5.4	14.1
Tissue IL-6; pg/g kidney tissue	Mean ± SE; LSD 0.05 = 4.074	57.30 ± 2.04^a	88.70 ± 1.67^d	78.08 ± 0.46^b	69.95 ± 0.37^c
	-test		−11.4	6.0	10.0
HbA1c; DCCT%	Mean ± SE; LSD 0.05 = 0.280	5.01 ± 0.07^a	7.81 ± 0.13^d	6.81 ± 0.07^b	6.15 ± 0.04^c
	-test		−15.3	5.4	12.7

Data are represented as mean ± SE. -test values; < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c, or d) are significantly different at < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at < 0.05. LSD: least significant difference.