Research Article

The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats

Table 3

Effect of treating diabetic rats with Moringa seeds powder for 4 weeks on liver enzymes (ALT, AST, and ALP), -amylase, fasting blood sugar, albumin, renal functions, and serum electrolytes.

ParametersStatisticsG1
−ve control
G2
+ve control
G3
50 mg
Moringa
G4
100 mg
Moringa

ALT
U/L
Mean ± SE
LSD 0.05 = 4.199
26.33 ± 1.45a27.50 ± 1.80a25.83 ± 1.70a26.66 ± 1.62a
-test−0.44NS1.74NS0.46NS

AST
U/L
Mean ± SE
LSD 0.05 = 9.452
27.00 ± 1.15a25.83 ± 1.301a25.66 ± 1.05a26.50 ± 0.95a
-test0.97NS0.09NS−0.37NS

ALP
U/L
Mean ± SE
LSD 0.05 = 29.741
114.17 ± 5.35a109.50 ± 4.21a111.83 ± 5.14a92.00 ± 16.57a
-test0.58NS−0.40NS0.91NS

-Amylase
U/L
Mean ± SE
LSD 0.05 = 12.986
47.16 ± 4.52a50.00 ± 3.58a48.00 ± 5.26a47.66 ± 3.77a
-test−0.62NS0.35NS0.33NS

Fasting blood sugar (FBS)
mg/dL
Mean ± SE
LSD 0.05 = 7.375
87.66 ± 2.76a266.50 ± 2.17d174.17 ± 1.86b148.83 ± 2.44c
-test−39.045.529.0

Albumin
g/dL
Mean ± SE
LSD 0.05 = 0.311
3.950 ± 0.13a1.400 ± 0.09d2.133 ± 0.06c2.76 ± 0.07b
-test−13.410.114.2

Data are represented as mean ± SE. -test values; < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c, or d) are significantly different at < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at < 0.05. LSD: least significant difference.