Polymorphonuclear Leukocyte Apoptosis Is Accelerated by Sulfatides or Sulfatides-Treated Salmonella Typhimurium Bacteria

Figure 6

β-galactosidase inhibitor PETG attenuates sulfatide-induced apoptosis. We cultured PMNLs for 2.5 h at 37°C without or with tested compounds (25 μg/mL sulfatides, 3 mM PETG; PETG was added 30 min prior to sulfatides). Then flow cytometry determined the percentage of Annexin V positive cells. Shown are the mean ± SD (a) and representative flow cytometric spectra (b) of four independent experiments.

(a)

(b)