Breast Cancer by Age at Diagnosis in the Gharbiah, Egypt, Population-Based Registry Compared to the United States Surveillance, Epidemiology, and End Results Program, 2004–2008
Table 1
Characteristics of Gharbiah, Egypt, and US SEER breast cancer cases, 2004–2008.
Gharbiah Cancer Registry and (%)
US SEER Registries and (%)
value
Mean age at diagnosis (SD)
51.0 (11.5)
61.4 (14.3)
<0.0001
Age in years
≤40
713 (18.7)
17,199 (6.3)
41–54
1,842 (48.2)
84,122 (30.8)
<0.0001
≥55
1,264 (33.1)
171,698 (62.9)
All ages combined
≤40 years of age
All ages combined
≤40 years of age
All ages combined
≤40 years of age
Grade
I
29 (1.0)
5 (0.9)
53,146 (21.5)
1,362 (8.6)
<0.0001
<0.0001
II
2,465 (88.4)
472 (88.2)
104,147 (42.1)
5,252 (33.0)
III
241 (8.6)
49 (9.2)
86,815 (35.1)
8,945 (56.2)
IV
55 (2.0)
9 (1.7)
3,448 (1.4)
369 (2.3)
Missing (% of total cases)
1,029 (26.9)
178 (25.0)
25,463 (9.3)
1,271 (7.3)
Hormone receptor
Positive
1,495 (77.3)
278 (77.4)
197,482 (79.6)
10,583 (66.9)
0.02
<0.0001
Negative
438 (22.7)
81 (22.6)
50,749 (20.4)
5,233 (33.1)
Missing (% of total cases)
1,886 (49.4)
354 (49.6)
24,788 (9.1)
1,383 (8.0)
Histology
Mucinous
36 (0.9)
6 (0.8)
6,430 (2.4)
259 (1.5)
<0.0001
<0.0001
Duct, NOS
2,812 (73.6)
530 (74.3)
191,138 (70.0)
13,652 (79.4)
Medullary
56 (1.5)
17 (2.4)
1,283 (0.5)
196 (1.1)
Lobular
155 (4.1)
14 (2.0)
22,155 (8.1)
495 (2.9)
Duct and lobular
57 (1.5)
22 (3.1)
19,992 (7.3)
892 (5.2)
Paget disease, mammary
43 (1.1)
14 (2.0)
1,003 (0.4)
99 (0.6)
Sarcomas; phyllodes tumor
46 (1.2)
14 (2.0)
703 (0.3)
127 (0.7)
Other
614 (16.1)
96 (13.5)
30,315 (11.1)
1,479 (8.6)
AJCC stage group
I
144 (4.7)
22 (3.9)
122,936 (48.1)
4,887 (30.1)
<0.0001
<0.0001
IIA
632 (20.8)
108 (19.4)
60,856 (23.8)
4,643 (28.6)
IIB
546 (18.0)
113 (20.3)
25,909 (10.1)
2,627 (16.2)
IIIA
701 (23.1)
135 (24.2)
17,205 (6.7)
1,910 (11.8)
IIIB
188 (6.2)
29 (5.2)
6,190 (2.4)
436 (2.7)
IIIC
444 (14.6)
87 (15.6)
7,914 (3.1)
777 (4.8)
IV
372 (12.3)
64 (11.5)
13,788 (5.4)
937 (5.8)
Missing (% of total cases)
792 (20.7)
155 (21.7)
18,221 (6.7)
982 (5.7)
Race
White
—
—
223,957 (82.0)
12,609 (73.3)
—
—
Black
—
—
27,630 (10.1)
2,580 (15.0)
American Indian/Alaska Native
—
—
1,256 (0.5)
108 (0.6)
Asian/Pacific Islander
—
—
18,702 (6.9)
1,761 (10.2)
Other/unknown
—
—
1,474 (0.5)
141 (0.8)
Hispanic
—
—
25,017 (9.2)
3,024 (17.6)
—
—
Non-Hispanic
—
—
248,092 (90.8)
14,175 (82.4)
Based on -test comparing Egyptian and US breast cancer cases, missing not included. Based on chi-square test comparing Egyptian and US breast cancer cases, missing not included. No cases missing histology; —: race/ethnicity unavailable in GCR.
