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BioMed Research International
Volume 2015, Article ID 392674, 21 pages
Review Article

Antitumor Phenylpropanoids Found in Essential Oils

1Núcleo de Farmácia, Universidade Federal de Sergipe, 58051-970 Lagarto, SE, Brazil
2Departamento de Farmácia, Universidade Federal de Sergipe, 49100-000 São Cristóvão, SE, Brazil
3Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, CP 5009, 58051-970 João Pessoa, PB, Brazil

Received 5 July 2014; Accepted 12 October 2014

Academic Editor: Gagan Deep

Copyright © 2015 Adriana Andrade Carvalho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The search for new bioactive substances with anticancer activity and the understanding of their mechanisms of action are high-priorities in the research effort toward more effective treatments for cancer. The phenylpropanoids are natural products found in many aromatic and medicinal plants, food, and essential oils. They exhibit various pharmacological activities and have applications in the pharmaceutical industry. In this review, the anticancer potential of 17 phenylpropanoids and derivatives from essential oils is discussed. Chemical structures, experimental report, and mechanisms of action of bioactive substances are presented.