Application of Long-Acting VLHL PAI-1 during Sutureless Partial Nephrectomy in Mice Reduces Bleeding

Figure 1

Plasma, solid line (no tPA, no VLHL PAI-1), clotted blood with mouse tPA alone (tPA 0.5 μg/mL), dash dot line, and clotted blood with mouse tPA (tPA 0.5 μg/mL) + VLHL PAI-1 (VLHL PAI-1  1.4 μg/mL), short dash line. Insert shows complex formation of VLHL PAI-1 with tPA. Lane 1, mouse tPA; lane 2, VLHL PAI-1; lane 3, mouse tPA + VLHL PAI-1.