Application of Long-Acting VLHL PAI-1 during Sutureless Partial Nephrectomy in Mice Reduces Bleeding

Table 2

Statistical significance of differences between different treatment groups.

	value; for blood loss	value for normalized blood loss
Group 1 (saline/saline) versus Group 2 (saline/PAI-1)	0.041	0.039
Group 1 (saline/saline) versus Group 3 (tPA/saline)	0.005	0.002
Group 3 (tPA/saline) versus Group 2 (saline/PAI-1)	NS	0.009
Group 3 (tPA/saline) versus Group 4 (tPA/PAI-1)	NS (0.051)	0.017

Blood loss was normalized by adjusting volume of blood by ratio of weight of the resected piece of kidney to remaining kidney.