Antioxidant, Hepatoprotective Potential and Chemical Profiling of Propolis Ethanolic Extract from Kashmir Himalaya Region Using UHPLC-DAD-QToF-MS
Table 4
Effect of different doses of propolis on in vivo antioxidant enzymes in INH-RIF induced hepatotoxicity.
GPx (nmol NADPH oxidized/min/mg protein)
XO (mg of uric acid formed/min/mg protein)
SOD (units/mg protein)
CAT (nmol H2O2 consumed/min/mg protein)
MDA (nmol of MDA formed/g tissue)
Group I
189.2 ± 3.877
2.072 ± 0.642
11.56 ± 0.422
4.707 ± 0.345
9.730 ± 0.567
Group II
90.04 ± 2.74
0.978 ± 0.58
7.237 ± 0.32
1.390 ± 0.33
21.31 ± 0.93
Group III
128.2 ± 2.71
1.743 ± 0.78
9.012 ± 0.32
2.718 ± 0.33
15.62 ± 0.51
Group IV
109.1 ± 2.24
1.892 ± 0.89
8.098 ± 0.29
2.663 ± 0.10
17.95 ± 0.48
Group V
102.6 ± 1.56
1.842 ± 0.50
8.833 ± 0.21
2.260 ± 0.12
16.80 ± 0.94
Values are mean ± S.E.M; = 6; , toxic versus normal, , extract treated groups versus toxic, , extract treated groups versus toxic, and , extract treated groups versus toxic; ns, not significant.
