BioMed Research International / 2015 / Article / Tab 1

Research Article

Development, Characterization, and In Vitro Biological Performance of Fluconazole-Loaded Microemulsions for the Topical Treatment of Cutaneous Leishmaniasis

Table 1

Rates of the components of FLU-unloaded MEs (F1, F2, and F3) and FLU-loaded MEs (F1D, F2D, and F3D). Oil phase is cholesterol; aqueous phase is 50 M of phosphate buffer at pH 7.4; surfactant is a mixture of soy phosphatidylcholine, polyoxyl-60 hydrogenated castor oil, and sodium oleate in a proportion of 3 : 8 : 6. LTS: liquid transparent system. VTS: viscous transparent system.

Formulations (% w/w)
F1F2F3F1DF2DF3D

Aqueous phase605040605040
Oil phase101010101010
Surfactant304050304050
Fluconazole 111
O : S ratio0,330,250,200,330,250,20
Phases’ classificationLTSVTSVTSLTSVTSVTS