Development, Characterization, and <i>In Vitro</i> Biological Performance of Fluconazole-Loaded Microemulsions for the Topical Treatment of Cutaneous Leishmaniasis

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Samples</td><td align="center">IC<sub>30</sub> (μM)</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">FLU</td><td align="center">—</td></tr><tr><td align="left">F1</td><td align="center">—</td></tr><tr><td align="left">F1D</td><td align="center">55.62 ± 5.79</td></tr><tr><td align="left">F2</td><td align="center">—</td></tr><tr><td align="left">F2D</td><td align="center">42.19 ± 3.12</td></tr><tr><td align="left">F3</td><td align="center">—</td></tr><tr><td align="left">F3D</td><td align="center">30.00 ± 2.83<sup>*</sup></td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td> <sup>*</sup>Significant statistical difference compared to the F1D and F2D formulations.<br/></td></tr></table>

IC<sub>30</sub> values against parasites for fluconazole samples and F1, F2, and F3 formulations with and without fluconazole. 

BioMed Research International

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Table 5

Table 5: Development, Characterization, and <i>In Vitro</i> Biological Performance of Fluconazole-Loaded Microemulsions for the Topical Treatment of Cutaneous Leishmaniasis 

Table 5 | Development, Characterization, and In Vitro Biological Performance of Fluconazole-Loaded Microemulsions for the Topical Treatment of Cutaneous Leishmaniasis 