Association of the NOTCH4 Gene Polymorphism rs204993 with Schizophrenia in the Chinese Han Population

Table 1

Analysis of the allele and genotype frequencies of a single SNP association.

Makers	Allele freq. (%)		P value	OR; (95% CI)	Genotype; ()			HWE; P value	Model	OR; (95% CI)	P value
Rs204993	G	A			GG	AG	AA
SCZ	41.3	58.7	0.223	1.115 (0.936–1.329)	78	210	155	0.182	Add	1.121 (0.937–1.342)	0.213
CTR	38.7	61.3			80	326	222		Dom	1.016 (0.788–1.311)	0.903
									Rec	1.464 (1.043–2.054)	0.027
Rs2071287	A	G			AA	AG	GG
SCZ	38.0	62.0	0.530	1.059 (0.886–1.264)	68	201	174	0.794	Add	1.058 (0.887–1.263)	0.532
CTR	36.7	63.3			83	295	250		Dom	1.022 (0.797–1.311)	0.861
									Rec	1.191 (0.842–1.682)	0.324

SCZ: schizophrenia; CTR: control; CI: confidence interval; OR: odds ratio.
Significant values and HWE values are shown in italic bold font.
values of the normal Chi-square statistics.
Add: addictive model; Dom: dominant model; Rec: recessive model.