Association of the NOTCH4 Gene Polymorphism rs204993 with Schizophrenia in the Chinese Han Population

Table 2

Analysis of sex-specific allele and genotype associations.

Markers and sex		Allele freq. (%)		P value	OR; (95% CI)	Genotype; ()			Model	OR; (95% CI)	value
rs204993		G	A			GG	AG	AA
F	SCZ	41.1	58.9	0.366	1.118; (0.878–1.422)	40	104	80	Add	1.120 (0.878–1.429)	0.362
	CTR	38.4	61.6			48	179	131	Dom	1.039 (0.734–1.471)	0.830
									Rec	3.242 (0.589–17.85)	0.145
M	SCZ	41.6	89.7	0.432	1.109; (0.857–1.433)	38	106	75	Add	1.118 (0.856–1.461)	0.414
	CTR	39.1	89.6			32	147	91	Dom	0.976 (0.670–1.422)	0.899
									Rec	1.561 (0.939–2.596)	0.084
rs2071287		T	C			TT	TC	CC
F	SCZ	39.3	60.7	0.098	1.229; (0.962–1.569)	36	104	84	Add	1.222 (0.960–1.555)	0.104
	CTR	34.5	65.5			45	157	156	Dom	1.287 (0.915–1.812)	0.148
									Rec	1.332 (0.829–2.14)	0.236
M	SCZ	36.8	63.2	0.358	1.885; (0.683–1.148)	32	97	90	Add	0.884 (0.680–1.148)	0.355
	CTR	39.6	60.4			44	138	94	Dom	0.766 (0.530–1.106)	0.154
									Rec	1.045 (0.629–1.737)	0.866

SCZ: schizophrenia; CTR: control; CI: confidence interval; OR: odds ratio.
values of the normal Chi-square statistics.
Add: addictive model; Dom: dominant model; Rec: recessive model.