Insufflation with Humidified and Heated Carbon Dioxide in Short-Term Laparoscopy: A Double-Blinded Randomized Controlled Trial
Table 2
Results.
Intervention group
Control group
Difference between medians
Significance
(95% confidence interval)
Rest pain
2 h: 5.5 (0–9.3)
2 h: 4.6 (0–9.5)
2 h: −0.3 (−1.4–0.9)
2 h: = 0.592
4 h: 2.7 (0–8.6)
4 h: 3.2 (0–8.3)
4 h: −0.1 (−0.9–0.8)
4 h: = 0.800
6 h: 0.8 (0–8.9)
6 h: 1.45 (0–7)
6 h: 0.2 (−0.4–0.7)
6 h: = 0.499
24 h: 0.75 (0–6.3)
24 h: 0.6 (0–7.6)
24 h: −0.1 (−0.6–0.2)
24 h: = 0.487
48 h: 0 (0–2.5)
48 h: 0 (0–4.5)
48 h: 0 (0)
48 h: = 0.641
Total: 10.2 (0–31.7)
Total: 11.1 (1.4–28.0)
Total: 0.05 (−2.8–3.1)
Total: = 0.977
Movement pain
2 h: 4.9 (0–9.6)
2 h: 4.6 (0–9.8)
2 h: −0.3 (−1.4–0.9)
2 h: = 0.608
4 h: 3.7 (0–8.6)
4 h: 3.8 (0–8.7)
4 h: −0.2 (−1.2–0.9)
4 h: = 0.779
6 h: 2.2 (0–8.9)
6 h: 2.3 (0–8.8)
6 h: −0.1 (−0.9–0.6)
6 h: = 0.749
24 h: 2.35 (0–8.4)
24 h: 2.5 (0–8.4)
24 h: 0.2 (−0.5–1.3)
24 h: = 0.539
48 h: 0.3 (0–5.1)
48 h: 0.5 (0–5.1)
48 h: 0 (−0.1–0.3)
48 h: = 0.562
Total: 14.2 (0.5–28.3)
Total: 13.65 (0.4–33.7)
Total: 0.7 (−3.1–4.2)
Total: = 0.719
Shoulder-tip pain
2 h: 0 (0–2.7)
2 h: 0 (0–8.7)
2 h: 0 (0)
2 h: = 0.278
Mean: 0.13
Mean: 0.65
4 h: 0 (0–5.4)
4 h: 0 (0–3.6)
4 h: 0 (0)
4 h: = 0.235
Mean: 0.21
Mean: 0.23
6 h: 0 (0–2.4)
6 h: 0 (0–7.2)
6 h: 0 (0)
6 h:
Mean: 0.09
Mean: 0.45
Upper side = 0.008
Two-sided = 0.016
24 h: 0 (0–8.3)
24 h: 0 (0–10)
24 h: 0 (0)
24 h: = 0.538
Mean: 1.24
Mean: 1.61
48 h: 0 (0–8.4)
48 h: 0.1 (0–10)
48 h: 0 (0–0.4)
48 h: = 0.155
Mean: 1.23
Mean: 1.62
Total:
Total:
Total:
Total:
0.35 (0–11.2)
1.6 (0–24.4)
0 (0–2.1)
Upper side = 0.037
Mean: 2.62
Mean: 4.73
Two-sided = 0.074
Cough pain
2 h: 4.1 (0–9.3)
2 h: 5.2 (0–9.7)
2 h: 0.2 (−0.9–1.5)
2 h: = 0.634
4 h: 3.5 (0–8.9)
4 h: 3.0 (0–9.4)
4 h: −0.4 (−1.5–0.7)
4 h: = 0.489
6 h: 2.4 (0–8.4)
6 h: 2.65 (0–9.0)
6 h: −0.2 (−1.1–0.8)
6 h: = 0.686
24 h: 2.6 (0–8.8)
24 h: 2.5 (0–9.3)
24 h: 0 (−0.9–1)
24 h: = 0.945
48 h: 0.4 (0–8.0)
48 h: 0.5 (0–6.9)
48 h: 0 (−0.3–0.3)
48 h: = 0.790
Total: 16 (1.9–29.8)
Total: 14.65 (1.2–35.1)
Total: −0.2 (−4–3.1)
Total: = 0.880
Temperature change*
−0.1 (−0.7–0.7)
−0.1 (−0.7–0.5)
= 0.768
Recovery room time
130 (70–1440)
135 (60–135)
0 (−20–20)
= 0.994
Length of stay
6 (3–9)
6 (5–9)
0 (0-0)
= 0.392
Morphine
10.5 (3.0–45.0)
13.5 (0–37.5)
3 (0–6)
Upper side = 0.027
on operation day
Mean: 12.51
Mean: 14.84
Two-sided = 0.054
Morphine
7.5 (0–46.5)
9 (0–36.0)
3 (0–4.5)
Upper side = 0.030
24 h postoperatively
Mean: 8.59
Mean: 11.36
Two-sided = 0.061
Morphine
0 (0–12.0)
0 (0–7.5)
0 (0)
= 0.896
48 h postoperatively
Mean: 0.52
Mean: 0.43
Total morphine consumption
16.5 (3.0–84.0)
24 (0–75)
6 (0–10.5)
Upper side = 0.0127
Mean: 21.65
Mean: 26.62
Two-sided = 0.0253
Bolus rejected
2 (0–53)
2 (0–31)
0 (−1–1)
= 0.574
on operation day
Mean: 5.02
Mean: 4.33
Bolus rejected
0 (0–16)
0 (0–13)
0 (0)
Upper side = 0.016
24 h postoperatively
Mean: 0.66
Mean: 1.96
Two-sided = 0.032
Bolus rejected
0 (0-1)
0 (0-1)
0 (0)
= 0.523
48 h postoperatively
Mean: 0.04
Mean: 0.02
Total bolus rejected
2 (0–55)
3 (0–37)
1 (0–2)
= 0.293
Mean: 5.48
Mean: 6.31
Values are given as median (range) or mean as stated. = two-sided if not otherwise stated; upper side = H1: tends to be greater than ; two-sided = H1: tends to be distributed differently to ; = control group. *ANOVA.
