Paclitaxel and Its Evolving Role in the Management of Ovarian Cancer

Figure 2

Chemical structure of paclitaxel. Paclitaxel consist of taxane ring with a four-membered oxetane side ring at positions C4 and C5 and an active homochiral ester side chain at C13 that binds to microtubules in a guanosine triphosphate (GTP) independent manner to induce cytotoxicity activity.