Morphological and Biomechanical Differences in the Elastase and AngII apoE^−/− Rodent Models of Abdominal Aortic Aneurysms

Figure 5

Histological staining reveals qualitative and semiquantitative differences in elastin and collagen content of AAAs. Representative MTC ((a), (b)) and VVG ((c), (d)) images of AAA tissue from a high concentration elastase rat ((a), (c)) and an AngII apoE^−/− mouse ((b), (d)). Normalized measurements of mean elastin and collagen content ((e), (f)) in high- () and low- () concentration-elastase rats (e) and AngII apoE^−/− mice () (f). Controls ( in each group) are sections with healthy regions. Scale bars: 200μm at low and 100μm at high magnification. Level of magnification: 8x ((a), (c)) and 2x ((b), (d)) relative to low magnification.

(a)

(b)

(c)

(d)

(e)

(f)