Morphological and Biomechanical Differences in the Elastase and AngII apoE^−/− Rodent Models of Abdominal Aortic Aneurysms

Table 1

Summary of values measured at days 0 and 28 in low- and high-concentration-elastase rats and AngII mice.

	Elastase rats		Elastase rats		AngII mice
	(0.44–0.48 U/mL)		(25 U/mL)		(1000 ng·kg^−1·min^−1)
	(mean ± SE ( = 6))		(mean ± SE ( = 5))		(mean ± SE ( = 7))
	Day 0	Day 28	Day 0	Day 28	Day 0	Day 28
Effective maximum diameter (mm)	1.48 ± 0.04	1.55 ± 0.05	1.43 ± 0.03	4.02 ± 0.29^*	1.01 ± 0.05	2.27 ± 0.15^*
Aortic maximum diameter (mm)	1.15 ± 0.09	1.46 ± 0.14	1.05 ± 0.03	3.85 ± 0.49^*	0.95 ± 0.05	2.06 ± 0.13^*
Volume/length (mm^2)	1.72 ± 0.06	2.06 ± 0.29	1.41 ± 0.06	8.65 ± 1.57^*	0.70 ± 0.08	2.76 ± 0.26^*
Length (mm)	6.92 ± 0.40		7.88 ± 0.83		7.07 ± 0.65
False lumen volume (mm^3)	NA	NA	NA	NA	0	11.1 ± 1.57^*
Circumferential cyclic strain (%)	17.28 ± 1.34	6.18 ± 0.72^*	12.67 ± 1.39	2.14 ± 0.27^*	12.6 ± 1.4	2.5 ± 0.61^*
Mean BFV (perfused region/AAA) (mm/s)	NA	230 ± 28.4	NA	85.3 ± 29.6°	NA	189 ± 99.9
Mean BFV (healthy region) (mm/s)	318 ± 11.3		370 ± 55.4	322 ± 41.9^*	374 ± 44.7	401 ± 57.3

Statistical significance shown for = 0.05: ^*versus the vessel measurement at day 0; versus healthy region measurement at day 28; °versus healthy region measurement at day 0.
Data are given as mean ± SE. BFV: blood flow velocity; NA: not applicable.