Sepsis and AKI in Clinical Emergency Room Patients: The Role of Urinary NGAL
Table 1
Patients demographics and clinical characteristics ().
Characteristics
Septic patients ()
Male sex (%)
97 (57.7)
Age (years)
68 ± 15.4
MBP
73.3 ± 23
Comorbidities (%)
Hypertension
85 (50.6)
Diabetes
44 (26.1)
Dyslipidemia
18 (10.7)
Cardiovascular disease
50 (29.7)
Liver disease
6 (3.5)
CKD
12 (7.1)
Baseline creatinine
0.82 ± 0.3
Noradrenaline use (%)
93 (55.3)
Classification of sepsis (%):
Sepsis
26 (15.4)
Severe sepsis
49 (29.1)
Septic shock
93 (55.3)
Source of infection (%):
Urine
30 (18)
Lung
81 (48.8)
Mechanical ventilation (%)
36 (21.4)
Blood transfusion (%)
13 (7.7)
Steroids use (%)
29 (17.2)
Time for antibiotics administration
<1 h (%)
83 (50.92)
>1 h (%)
80 (49.08)
AKI (%)
121 (72.02)
At admission
87 (71.9)
During hospitalization
34 (28.1)
Urine output in 24 h (mL)
900 (450–1425)
Urine output (mL/kg/h)
0.70 (0.4–1.05)
APACHE II
19.67 ± 7.11
Dialysis (%)
15 (8.93)
Outcome (%)
Discharge
92 (55.7)
Death
73 (44.2)
Values expressed as mean and standard deviation or median and interquartile range. AKI: acute kidney injury, MBP: mean blood pressure, CKD: chronic kidney disease, ATN-ISS: acute tubular necrosis individual severity score, and ICU: intensive care unit.