Antiresistin RNA Oligonucleotide Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease in Mice through Attenuating Proinflammatory Cytokines

Figure 5

Effects of antiresistin RNA oligo on mRNA expression. (a) TNF-α, IL-6, leptin, and adiponectin mRNA expression in adipose tissue; (b) hepatic mRNA expression of TNF-α, IL-6, PEPCK, and SREBP-1c in chow fed mice and HFD fed mice treated with a control oligo or antiresistin oligo. Data are mean ± SE (). and versus chow fed mice; versus HFD-Con-oligo mice.

(a) In adipose tissue

(b) In liver tissue