Research Article

The Ethanolic Extract of Taiwanofungus camphoratus (Antrodia camphorata) Induces Cell Cycle Arrest and Enhances Cytotoxicity of Cisplatin and Doxorubicin on Human Hepatocellular Carcinoma Cells

Table 1

Half-maximal inhibitory concentration (IC50) analysis on Hep3B and HepJ5 cells treated with TCEE alone or in combination with cisplatin or doxorubicin. The IC50 values of TCEE on Hep3B and HepJ5 were analyzed on cell viability data obtained from Figure 1 by using the CalcuSyn software, and the IC50 values of cisplatin and doxorubicin with TCEE were from Figure 3.

Hep3BHepJ5

TCEE (mg/mL)0.480.91

Combined treatment with conventional chemotherapy agents
TCEE (mg/mL)
00.200.5

Cisplatin (μM)5.382.294.572.82
Doxorubicin (μM)2.370.911.280.51