Table 1: Half-maximal inhibitory concentration (IC50) analysis on Hep3B and HepJ5 cells treated with TCEE alone or in combination with cisplatin or doxorubicin. The IC50 values of TCEE on Hep3B and HepJ5 were analyzed on cell viability data obtained from Figure 1 by using the CalcuSyn software, and the IC50 values of cisplatin and doxorubicin with TCEE were from Figure 3.


TCEE (mg/mL)0.480.91

Combined treatment with conventional chemotherapy agents
TCEE (mg/mL)

Cisplatin (μM)5.382.294.572.82
Doxorubicin (μM)2.370.911.280.51