A Novel Microbisporicin Producer Identified by Early Dereplication during Lantibiotic Screening

Figure 1

MS-HPLC profiles of the F31/11 broth screening extract: (a) MS trace in negative and positive mode; (b) bioautography: each HPLC fraction was tested versus S. aureus MRSA L1400, MSSA L100, and L-form L3751 in dose dilution; (c) MS spectrum of the peak eluting at 11.7 min in negative and positive mode; (d) UV spectrum of the peak eluting at 11.7 min; (e) MS spectrum of the peak eluting at 12.2 min in negative and positive mode; (f) UV spectrum of the peak eluting at 12.2 min. In UV spectra, the values of the maximum and of the shoulder are indicated.

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