Research Article

A Novel Microbisporicin Producer Identified by Early Dereplication during Lantibiotic Screening

Table 2

Antimicrobial activity of F31/11 crude extract in comparison to planosporicin, actagardine, microbisporicin, mersacidin, and nisin standards. MICs were determined by broth microdilution assay [27].

StrainMIC (mg/L)
PlanosporicinActagardineMicrobisporicinMersacidin NisinF31/11

L100 S. aureus ATCC6538P232≤0.1340.54
L3751 S. aureus L-form>128>128>1286416>128
L1400 S. aureus MRSA1616≤0.13828
L49 S. pyogenes <12<1n.dn.d1
L47 E. coli >128>128>128n.d>128>128
L145 C. albicans >128>128>128n.d>128>128