Research Article

Drug Susceptibility Testing of 31 Antimicrobial Agents on Rapidly Growing Mycobacteria Isolates from China

Table 4

The MIC range, MIC50, and MIC90 (μg/mL) per species of rapidly growing mycobacterial isolates for all the antibacterial agents tested.

DrugsM. abscessus ()M. fortuitum ()Other species ()
MIC rangeMIC50MIC90MIC rangeMIC50MIC90MIC rangeMIC50MIC90

RFP 0.5–>256161281–>256128>2562–828
INH2–>256>256>256 2–>256>256>25616–>256>256>256
EMB1–>256>256 >25632–>256256>256128–>256>256>256
SM<0.25–>256322568–>256321284–643264
AM0.06–16480.06–16240.25–>3248
KN0.25–>324320.5–>328162–>3216>32
CPM0.03–16180.03–20.520.03–32416
TOB<0.25–648320.5–324320.5–32416
OF0.06–328160.06–324160.03–80.58
CIP0.03–32440.06–8480.13–824
LEV0.03–32880.06–8280.13–1648
SPA0.03–324160.03–162160.06–160.252
MXF0.03–16240.03–8140.06–80.52
LNZ0.5–>644160.5–164160.25–1648
CLO0.06–>320.2580.03–160.2520.06–>320.54
SMZ0.5–>25632>2564–12816644–>25616256
MIN<0.25–>25616321–25616642–321632
DOX<0.25–>2561632<0.25–256642561–64832
TIG<0.25–822<0.25–844<0.25–10.51
CLR0.03–>320.13>320.06–>320.25160.03–>3218
AZM0.03–>320.5>320.13–>322>32 0.13–>32132
ROX0.03–>320.25>32 0.13–321320.03–16816
AMC0.5–>256>256>256256–>256>256 >2561–>256>256>256
FOX4–>2566425616–>2563212832–>256128256
CMZ1–12816648–6416648–>2563264
MEM<0.25–>2568128<0.25–>25682560.5–32432
RPT0.03–>328321–>328>320.06–32216
RBT0.03–>321160.5–>322160.03–414
DAP1–>256161282–>256641284–2561664
THI 8–>256>256>256128–>256>256>256 128–>256>256>256
PASI2–>256256>2568–>256>256 >25616–>256>256>256

Note: : number of strains tested.