Osteoprotective Effect of Cordycepin on Estrogen Deficiency-Induced Osteoporosis In Vitro and In Vivo

Table 3

Effect of cordycepin on the activity of various enzymes.

Different groups	GPx	GR	GST	CAT	Na^+K^+ATPase
Sham	15.98 ± 1.23^***	35.55 ± 2.51^***	17.00 ± 1.22^**	7.11 ± 0.33^*	4.52 ± 0.32^**
OVX	8.01 ± 0.42	20.88 ± 2.11	10.07 ± 1.11	4.22 ± 0.13	2.00 ± 0.13
Cordycepin-20	13.16 ± 1.32^**	29.01 ± 2.21^***	13.66 ± 0.90^*	5.78 ± 0.20^*	4.11 ± 0.22^*
Cordycepin-10	9.10 ± 1.02	26.00 ± 2.22	13.00 ± 0.91	4.70 ± 0.21	3.51 ± 0.23
Cordycepin-5	8.16 ± 1.31	21.21 ± 2.20	10.10 ± 0.92	4.28 ± 0.33^*	2.10 ± 0.11

Values are shown as means ± SEM. ^*P < 0.05 versus OVX group, ^**P < 0.01 versus OVX group, and ^***P < 0.001 versus OVX group.