Prenatal Diagnosis of Central Nervous System Anomalies by High-Resolution Chromosomal Microarray Analysis

Figure 1

Microarray testing results. The CNVs of Cases 1, 3, 6, and 7 were detected by aCGH. (a)–(d) showed aCGH results of Cases 1, 3, 6, and 7, respectively. (a) A 3.44-Mb deletion within chromosome 7q in Case 1. (b) A 3.25-Mb deletion in chromosome 2q in Case 3 harbored four OMIM genes. (c) A 4.03-Mb deletion of chromosome 19p in Case 6. (d) A 2.79-Mb deletion in chromosome 4q35.2 in Case 7. The respective chromosomes are shown and labeled. Signal intensity is plotted on a scale, such that a normal copy number gives a value of 0. Chromosomal deletions are denoted by leftward deviation of the central line (marked by red boxes).

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