Research Article

Organotypic Cultures of Intervertebral Disc Cells: Responses to Growth Factors and Signaling Pathways Involved

Table 1

Regulation of PDGF-stimulated DNA synthesis in monolayer NP cultures by CSA.

CSA concentration (μg/mL)PDGF-BB concentration (ng/mL)
010

034.5% (±2.5)58.1% (±2.1)
25010.2% (±3.6)46.2% (±10.2)

Percentage of BrdU-positive nuclei (mean ± SEM from three independent cultures; three representative fields were counted in each culture).