Table 3: Summary of the principal parameters influenced by simulated microgravity and hypergravity in different types of ECs.

MicrogravityHypergravity
Endothelial cell line EA.hy926Dermal HMECHUVECPAECBAECEndothelial cell line EA.hy926HUVECCVECBAEC

Migration==/↑NDNDND
ProliferationNDND (=/↑)=ND
Apoptosis====/↓===
NO synthesisNDNDNDND
Cytoskeletal rearrangements++++++++++++++++++++++++++

Legend: ↑, increased; ↓, decreased; =, no change; ND, not determined; ++ and +++, highly and strongly upregulated.