Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 451912, 11 pages
http://dx.doi.org/10.1155/2015/451912
Research Article

Multiple Sclerosis in Older Adults: The Clinical Profile and Impact of Interferon Beta Treatment

1Department of Medicine, Division of Neurology and Brain Research Centre, UBC Hospital, University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC, Canada V6T 2B5
2Department of Statistics, University of British Columbia, 3182 Earth Sciences Building, 2207 Main Mall, Vancouver, BC, Canada V6T 1Z4
3College of Pharmacy and Nutrition, University of Saskatchewan, 110 Science Place, Saskatoon, SK, Canada S7N 5C9
4Department of Public Health Sciences, Karolinska Institutet, 171 77 Stockholm, Sweden

Received 5 September 2014; Revised 28 February 2015; Accepted 2 March 2015

Academic Editor: Eberval G. Figueiredo

Copyright © 2015 Afsaneh Shirani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [13 citations]

The following is the list of published articles that have cited the current article.

  • Mohammad Ehsanul Karim, John Petkau, Paul Gustafson, Robert W Platt, and Helen Tremlett, “Comparison of statistical approaches dealing with time-dependent confounding in drug effectiveness studies,” Statistical Methods in Medical Research, pp. 096228021666855, 2016. View at Publisher · View at Google Scholar
  • Mohammad Ehsanul Karim, Paul Gustafson, John Petkau, and Helen Tremlett, “Comparison of Statistical Approaches for Dealing With Immortal Time Bias in Drug Effectiveness Studies,” American Journal of Epidemiology, pp. kwv445, 2016. View at Publisher · View at Google Scholar
  • Rachel E Klaren, Emerson Sebastiao, Chung-Yi Chiu, Dominique Kinnett-Hopkins, Edward McAuley, and Robert W Motl, “Levels and Rates of Physical Activity in Older Adults with Multiple Sclerosis.,” Aging and disease, vol. 7, no. 3, pp. 278–84, 2016. View at Publisher · View at Google Scholar
  • Shaik Ahmed Sanai, Vasu Saini, Ralph H. B. Benedict, Robert Zivadinov, Barbara E. Teter, Murali Ramanathan, and Bianca Weinstock-Guttman, “Aging and multiple sclerosis,” Multiple Sclerosis Journal, vol. 22, no. 6, pp. 717–725, 2016. View at Publisher · View at Google Scholar
  • Robert W. Motl, Emerson Sebastião, Rachel E. Klaren, Elizabeth A. L. Stine-Morrow, Brent Roberts, and Edward McAuley, “Physical activity and healthy aging with multiple sclerosis—Literature review and research directions,” European Neurological Review, vol. 12, no. 1, pp. 29–33, 2016. View at Publisher · View at Google Scholar
  • Raed Alroughani, Saeed Akhtar, Samar Ahmed, Raed Behbehani, and Jasem Al-Hashel, “Is time to reach EDSS 6.0 faster in patients with late-onset versus young-onset multiple sclerosis?,” PLoS ONE, vol. 11, no. 11, 2016. View at Publisher · View at Google Scholar
  • Nages Nagaratnam, Kujan Nagaratnam, Gary Cheuk, Nages Nagaratnam, Kujan Nagaratnam, and Gary Cheuk, “Multiple Sclerosis,” Geriatric Diseases, pp. 1–6, 2017. View at Publisher · View at Google Scholar
  • Emerson Sebastião, Edward McAuley, Ryosuke Shigematsu, and Robert W. Motl, “Feasibility study design and methods for a home-based, square-stepping exercise program among older adults with multiple sclerosis: The SSE-MS project,” Contemporary Clinical Trials Communications, 2017. View at Publisher · View at Google Scholar
  • Emanuele D’Amico, Tjalf Ziemssen, and Salvatore Cottone, “To stop or not to stop disease modifying therapies in secondary progressive multiple sclerosis, that is the question,” Expert Review of Neurotherapeutics, pp. 1–3, 2017. View at Publisher · View at Google Scholar
  • Mohammad Ehsanul Karim, and Robert W. Platt, “Estimating inverse probability weights using super learner when weight-model specification is unknown in a marginal structural Cox model context,” Statistics in Medicine, 2017. View at Publisher · View at Google Scholar
  • Alessia Piermattei, Chaya Brodie, Eytan R. Barnea, Giuseppe Migliara, Martin Mueller, Michael J. Paidas, and Francesco Ria, “PIF* promotes brain re-myelination locally while regulating systemic inflammation- clinically relevant multiple sclerosis M.smegmatis model,” Oncotarget, vol. 8, no. 13, pp. 21834–21851, 2017. View at Publisher · View at Google Scholar
  • Laura Dumitrescu, Cris S. Constantinescu, and Radu Tanasescu, “Recent developments in interferon-based therapies for multiple sclerosis,” Expert Opinion on Biological Therapy, pp. 1–16, 2018. View at Publisher · View at Google Scholar
  • Nages Nagaratnam, Kujan Nagaratnam, Gary Cheuk, Nages Nagaratnam, Kujan Nagaratnam, and Gary Cheuk, “Multiple Sclerosis,” Geriatric Diseases, pp. 337–341, 2018. View at Publisher · View at Google Scholar