Clinical Study
Improvement of BMI after Lifestyle Intervention Is Associated with Normalisation of Elevated ELF Score and Liver Stiffness in Obese Children
Table 3
Anthropometric measures and laboratory values at baseline and after 12 months.
| | | Obese study population, baseline, median (range) | | Obese study population, follow-up, median (range) | |
| BMI | | | | | | All participants | 39 | 28.48 (20.9–42.7) | | | | Patients with paired follow-up data | 36 | 28.13 (20.9–42.7) | 36 | 27.79 (19.2–44.9) | 0.925 | BMI percentile | | | | | | All participants | 39 | 99.1 (90.7–99.9) | | | | Patients with paired follow-up data | 36 | 98.95 (90.7–99.9) | 36 | 98.55 (81.3–99.9) | 0.003 | BMI-SDS | | | | | | All participants | 39 | 2.36 (1.33–3.58) | | | | Patients with paired follow-up data | 36 | 2.31 (1.33–3.58) | 36 | 2.25 (0.90–3.68) | 0.028 | WHtR | | | | | | All participants | 39 | 0.61 (0.51–0.74) | | | | Patients with paired follow-up data | 33 | 0.60 (0.51–0.73) | 33 | 0.60 (0.47–0.77) | 0.914 | Triglyceride | | | | | | All participants | 39 | 80 mg/dL (25–317) | | | | Patients with paired follow-up data | 36 | 81 mg/dL (25–317) | 36 | 61 mg/dL (22–328) | 0.020 | Total cholesterol | | | | | | All participants | 39 | 177 mg/dL (108–289) | | | | Patients with paired follow-up data | 36 | 180 mg/dL (108–289) | 36 | 166 mg/dL (108–265) | 0.090 | LDL cholesterol | | | | | | All participants | 39 | 110 mg/dL (44–225) | | | | Patients with paired follow-up data | 36 | 110 mg/dL (44–225) | 36 | 104 mg/dL (48–207) | | Fasting glucose | | | | | | All participants | 39 | 84 mg/dL (69–107) | | | | Patients with paired follow-up data | 36 | 84 mg/dL (69–107) | 36 | 81 mg/dL (67–97) | 0.002 | HOMA index | | | | | | All participants | 37 | 3.2 (1.1–7.4) | 31 | 2.4 (0.3–7.1) | | Patients with paired follow-up data | 29 | 3.2 (1.1–7.4) | 29 | 2.3 (0.3–7.1) | 0.091 | Transient elastography | | | | | | All participants | 28 | 5.9 kPa (3.4–8.3) | 21 | 4.5 kPa (2.4–9.6) | | Patients with paired follow-up data | 18 | 5.0 kPa (3.4–8.3) | 18 | 4.4 kPa (2.4–9.6) | 0.076 | Enhanced liver fibrosis (ELF) test | | | | | | All participants | 33 | 9.0 (7.87–9.60) | 27 | 8.51 (7.15–9.55) | | Patients with paired follow-up data | 25 | 8.9 (7.87–9.60) | 25 | 8.51 (7.15–9.55) | 0.02 |
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BMI: body mass index; WHtR: waist-to-height ratio; HOMA: homeostasis model assessment.
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