BioMed Research International / 2015 / Article / Tab 3

Clinical Study

Improvement of BMI after Lifestyle Intervention Is Associated with Normalisation of Elevated ELF Score and Liver Stiffness in Obese Children

Table 3

Anthropometric measures and laboratory values at baseline and after 12 months.

Obese study population,
baseline,
median (range)
Obese study population,
follow-up,
median (range)

BMI
 All participants3928.48 (20.9–42.7)
 Patients with paired follow-up data3628.13 (20.9–42.7)3627.79 (19.2–44.9)0.925
BMI percentile
 All participants3999.1 (90.7–99.9)
 Patients with paired follow-up data3698.95 (90.7–99.9)3698.55 (81.3–99.9)0.003
BMI-SDS
 All participants392.36 (1.33–3.58)
 Patients with paired follow-up data362.31 (1.33–3.58)362.25 (0.90–3.68)0.028
WHtR
 All participants390.61 (0.51–0.74)
 Patients with paired follow-up data330.60 (0.51–0.73)330.60 (0.47–0.77)0.914
Triglyceride
 All participants3980 mg/dL (25–317)
 Patients with paired follow-up data3681 mg/dL (25–317)3661 mg/dL (22–328)0.020
Total cholesterol
 All participants39177 mg/dL (108–289)
 Patients with paired follow-up data36180 mg/dL (108–289)36166 mg/dL (108–265)0.090
LDL cholesterol
 All participants39110 mg/dL (44–225)
 Patients with paired follow-up data36110 mg/dL (44–225)36104 mg/dL (48–207)
Fasting glucose
 All participants3984 mg/dL (69–107)
 Patients with paired follow-up data3684 mg/dL (69–107)3681 mg/dL (67–97)0.002
HOMA index
 All participants373.2 (1.1–7.4)312.4 (0.3–7.1)
 Patients with paired follow-up data293.2 (1.1–7.4)292.3 (0.3–7.1)0.091
Transient elastography
 All participants285.9 kPa (3.4–8.3)214.5 kPa (2.4–9.6)
 Patients with paired follow-up data185.0 kPa (3.4–8.3)184.4 kPa (2.4–9.6)0.076
Enhanced liver fibrosis (ELF) test
 All participants339.0 (7.87–9.60)278.51 (7.15–9.55)
 Patients with paired follow-up data258.9 (7.87–9.60)258.51 (7.15–9.55)0.02

BMI: body mass index; WHtR: waist-to-height ratio; HOMA: homeostasis model assessment.

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