Review Article
Vitamin Supplementation as Possible Prophylactic Treatment against Migraine with Aura and Menstrual Migraine
Table 2
Characteristics of clinical trials conducted among migraine patients using vitamins B6, B9, and B12.
| Study location | Control | Placebo | Duration of administration | Outcomes | value | Reference | Dose | Sample size | Dose Sample size |
| Australia | Vitapop tablet containing B6 (25 mg), B9 (2 mg) & B12 (400 μg) once daily | 37 | Compared with baseline |
6 months | Migraine disability | 0.010 | | Frequency of headache | 0.040 | [36] | Headache pain severity | 0.002 | |
| Australia | Vitapop tablet containing B6 (25 mg), B9 (2 mg) & B12 (400 μg) once daily | 103 | Compared with baseline |
6 months | Migraine disability | 0.022 | | Frequency of headache | 0.460 | [45] | Headache pain severity | 0.017 | |
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