Identification of Novel Potential Vaccine Candidates against Tuberculosis Based on Reverse Vaccinology

Figure 3

C-ImmSim simulation of an immunization experiment using Erp protein. An immunogenic molecule (Erp) was inoculated at time zero. Different cellular populations showed stimulation with Erp antigen at 1.2 months after one dose immunization. (a) B-cell population, (b) B-cell population per state, (c) Th cell population, (d) Th cell population per state, (e) Tc cell population, (f) Tc cell population per state, (g) macrophages population per state, (h) dendritic cell population per state, (i) epithelial cell population, and (j) antibody titers.

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