Cholinergic Synaptic Transmissions Were Altered after Single Sevoflurane Exposure in Drosophila Pupa

Figure 3

Cholinergic mEPSCs were altered 24 h after sevoflurane exposure. (a) While neurons were held on −70 mV in voltage-clamp mode, mEPSCs traces were recorded in each group in the presence of TTX and PTX. (b) 24 h after sevoflurane exposure, frequency of mEPSc was significantly reduced when compared to control (, , ), (c) while the amplitude of mEPSCs was not changed (, , ).

(a)

(b)

(c)