Effect of Spirulina Intervention on Oxidative Stress, Antioxidant Status, and Lipid Profile in Chronic Obstructive Pulmonary Disease Patients
Table 4
Effect of spirulina intervention at (500 × 2) mg dose on serum content of oxidants and antioxidants and on the activity of burst enzymes in COPD patients.
Parameters
0 days (mean ± SD)
30 days (mean ± SD)
60 days (mean ± SD)
value
value
Malondialdehyde (MDA) (nmoL/mL)
3.78 ± 0.24
3.32 ± 0.26
2.99 ± 0.22
85.083
0.000*
Lipid hydroperoxide (nmoL/mL)
3.63 ± 0.19
3.41 ± 0.21
2.79 ± 0.22
136.057
0.000*
Catalase (kU/L)
31.53 ± 8.41
33.33 ± 8.30
34.05 ± 8.08
0.740
0.480
Superoxide dismutase (SOD) (U/mL)
67.25 ± 6.43
70.64 ± 6.20
75.89 ± 5.34
15.742
0.000*
Glutathione-S-transferase (GST) (U/mL)
28.41 ± 4.02
29.14 ± 4.05
30.95 ± 3.50
3.408
0.038*
Glutathione (GSH) (nmoL/mL)
279.3 ± 23.26
302.28 ± 18.42
332.61 ± 13.61
60.399
0.000*
Vitamin C (mg/dL)
0.76 ± 0.07
0.83 ± 0.06
0.92 ± 0.05
52.971
0.000*
Cholesterol (mg/dL)
167.22 ± 10.33
162.15 ± 9.03
152.08 ± 7.95
21.233
0.000*
Triglyceride (TG) (mg/dL)
172.10 ± 14.44
169.55 ± 14.15
167.18 ± 12.22
0.975
0.381
High density lipoprotein (HDL) (mg/dL)
42.21 ± 5.17
42.72 ± 5.12
43.45 ± 5.20
0.436
0.648
Statistically significant. Comparisons are made between day 0 versus day 30 and day 0 versus day 60.
