Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics
Table 2
Clinical trials using blood/plasma or serum carbohydrate analysis to diagnose and monitor cancer. Information on recent clinical trials (https://clinicaltrials.gov/) that involve analysis of glycosylation-based biomarkers in blood components to monitor and diagnose various cancers. Status of trials was correct at time of submission (April 2015).
Trial title
Description of trial
Statu
Clinicaltrials.gov identifier
Glycoprotein and Glycan in Patients with Stage I, Stage II, and Stage III or Stage IV Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes
Studying samples of tumor tissue and blood from patients to identify cancer biomarkers; the current primary objectives of this study are to detect the presence of T-synthase or COSMIC. Measuring the level of staining for Tn and STn antigens as well as measuring the differences in expression of 50 different genes on a customized glycogen array and differences in 10 carbohydrate structures using a customized glycan array.
The Association between Alpha 1 Acid Glycoprotein Level and Outcome Metastatic Cancer Treated with Docetaxel
The association between the baseline plasma level of alpha 1 acid glycoprotein and progression-free survival of docetaxel based therapies in patients with metastatic nonsmall cell lung carcinoma, breast cancer, gastric cancer, prostate cancer, and bladder cancer.
