{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3

Figure 1

MIAM inhibited the proliferation of Bel-7402 and Bel-7402/5FU cells in vitro. HCC cells seeded in the 96-well plates were exposed to MIAM and ADR for up to 72 h. Viable cells were estimated by the MTT assay and denoted as a percentage of untreated controls at the concurrent time point. The bars indicate mean ± S.D. (). , versus the vehicle control.

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