Expression Profile of Sonic Hedgehog Pathway Members in the Developing Human Fetal Brain

Figure 1

Expression pattern of SHH pathway members in the normal human fetal cortex. Immunohistochemistry for (a) Shh, (b) Patched, (c) Smoothened, (d) Gli1, (e) Gli2, and (f) Gli3 in superficial telencephalic cortical layers including MZ (marginal zone), CP (cortical plate), SP (subplate), and IZ (intermediate zone) (examples are depicted from a 14th week of gestation fetus; original magnification: 200x).

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